Ceftriaxone and its Use in an Antibiotic Adjuvant Entity
Ceftriaxone gram negative, on its own is used to treat a wide variety of bacterial infections. Sometimes it is even used to treat life-threatening diseases, such as meningitis, and also to prevent infections in people having certain types of surgery. It is a cephalosporin antibiotic, and works by fighting the bacteria present in the body.
It is usually administered through an IV, injected into the vein or a muscle. It is advised to let medical professionals handle ceftriaxone delivery, if you are not proficient with how to operate the IV and proper disposal of needles and tubings.
Some common side effects of ceftriaxone
The use of ceftriaxone gram negative usually does not involve any serious side effects. Some redness, pain, or swelling at the area of injection may occur, but the effects subside rather quickly. If, however, the pain or swelling lasts or worsens, contact a doctor immediately.
Some serious side effects of ceftriaxone gram negative may include unusual tiredness, easy bleeding or bruising, and signs of kidney problems. If you notice any of these symptoms, contact the doctor immediately. Also, do not use anti-diarrheal or narcotic pain medicines if you have any of the aforementioned symptoms, it may only make the condition worse.
Management of bloodstream infections and pneumonia using an antibiotic adjuvant entity
Other than the regular antibiotic uses of ceftriaxone gram negative, clinical tests have shown that its addition with disodium edetate and sulbactam has resulted in effective treatment of ventilator associated pneumonia. This new antibiotic adjuvant entity has been tested on over 100 patients according to a particular study, where around 87% of patients were found sensitive to this antibiotic adjuvant entity. Since ventilator associated pneumonia is one of the most serious nosocomial infections related to ICUs, it is obvious to see the importance being laid on the treatment of this disease.
This antibiotic adjuvant entity can also be used to treat bloodstream infections. These bacterial conditions come under the category of multi drug resistant nosocomial gram negative infections. Therefore, ceftriaxone gram negative could not be used to treat them on its own. However, the combination of ceftriaxone with sulbactam and disodium edetate, creating an antibiotic adjuvant entity, has proven to be successful in treating various MDR nosocomial gram negative infections.
As compared to other drugs and compounds, this antibiotic adjuvant entity has shown better results in the management of various MDR nosocomial infections. Many patients who did not respond to other drugs such as meropenem, gave positive results when tested with the AAE.
Ceftriaxone gram negative can indeed be used to treat a variety of bacterial infections, but when combined to form an antibiotic adjuvant entity, its power can be increased manifold to treat the most serious of nosocomial infections.
